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Identification of potential target genes of USP22 via ChIP-seq and RNA-seq analysis in HeLa cells

The ubiquitin-specific protease 22 (USP22) is an oncogene and its expression is upregulated in many types of cancer. In the nucleus, USP22 functions as one subunit of the SAGA to regulate gene transcription. However, the genome-wide USP22 binding sites and its direct target genes are yet clear. In t...

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Detalhes bibliográficos
Publicado no:Genet Mol Biol
Main Authors: Gong, Zhen, Liu, Jianyun, Xie, Xin, Xu, Xiaoyuan, Wu, Ping, Li, Huimin, Wang, Yaqin, Li, Weidong, Xiong, Jianjun
Formato: Artigo
Idioma:Inglês
Publicado em: Sociedade Brasileira de Genética 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082230/
https://ncbi.nlm.nih.gov/pubmed/30088609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1678-4685-GMB-2017-0164
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