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Pirarubicin reduces USP22 expression by inhibiting CREB-1 phosphorylation in HeLa cells

The expression of ubiquitin specific peptidase 22 (USP22) is upregulated in several types of cancer, and has been implicated in tumorigenesis. Pirarubicin (THP), an anthracycline antineoplastic drug, can induce apoptosis of several types of cancer cells. However, the molecular mechanisms underlying...

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Bibliografski detalji
Izdano u:Exp Ther Med
Glavni autori: Zhou, Xiaoou, Gan, Lijun, Liu, Jianyun, Xie, Xin, Wang, Tao, Xiong, Jianjun
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468931/
https://ncbi.nlm.nih.gov/pubmed/31007754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7447
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