Development of DNA Aptamers to Native EpCAM for Isolation of Lung Circulating Tumor Cells from Human Blood

We selected DNA aptamers to the epithelial cell adhesion molecule (EpCAM) expressed on primary lung cancer cells isolated from the tumors of patients with non-small cell lung cancer using competitive displacement of aptamers from EpCAM by a corresponding antibody. The resulting aptamers clones showe...

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Udgivet i:Cancers (Basel)
Main Authors: Zamay, Galina S., Kolovskaya, Olga S., Ivanchenko, Tatiana I., Zamay, Tatiana N., Veprintsev, Dmitry V., Grigorieva, Valentina L., Garanzha, Irina I., Krat, Alexey V., Glazyrin, Yury E., Gargaun, Ana, Lapin, Ivan N., Svetlichnyi, Valery A., Berezovski, Maxim V., Kichkailo, Anna S.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468627/
https://ncbi.nlm.nih.gov/pubmed/30871104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030351
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