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A general computational approach to predicting synergistic transcriptional cores that determine cell subpopulation identities

Advances in single-cell RNA-sequencing techniques reveal the existence of distinct cell subpopulations. Identification of transcription factors (TFs) that define the identity of these subpopulations poses a challenge. Here, we postulate that identity depends on background subpopulations, and is dete...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Okawa, Satoshi, del Sol, Antonio
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468312/
https://ncbi.nlm.nih.gov/pubmed/30820550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz147
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