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Cannabinoid CB(1) and CB(2) receptor mechanisms underlie cannabis reward and aversion in rats

BACKGROUND AND PURPOSE: Endocannabinoids are critically involved in brain reward functions, mediated by activation of CB(1) receptors, reflecting their high density in the brain. However, the recent discovery of CB(2) receptors in the brain, particularly in the midbrain dopamine neurons, has challen...

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Dades bibliogràfiques
Publicat a:Br J Pharmacol
Autors principals: Spiller, Krista J., Bi, Guo‐hua, He, Yi, Galaj, Ewa, Gardner, Eliot L., Xi, Zheng‐Xiong
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468271/
https://ncbi.nlm.nih.gov/pubmed/30767215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14625
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