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Cannabinoid CB(1) and CB(2) receptor mechanisms underlie cannabis reward and aversion in rats

BACKGROUND AND PURPOSE: Endocannabinoids are critically involved in brain reward functions, mediated by activation of CB(1) receptors, reflecting their high density in the brain. However, the recent discovery of CB(2) receptors in the brain, particularly in the midbrain dopamine neurons, has challen...

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Bibliographic Details
Published in:Br J Pharmacol
Main Authors: Spiller, Krista J., Bi, Guo‐hua, He, Yi, Galaj, Ewa, Gardner, Eliot L., Xi, Zheng‐Xiong
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468271/
https://ncbi.nlm.nih.gov/pubmed/30767215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14625
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