Cannabinoid CB(1) and CB(2) receptor mechanisms underlie cannabis reward and aversion in rats

BACKGROUND AND PURPOSE: Endocannabinoids are critically involved in brain reward functions, mediated by activation of CB(1) receptors, reflecting their high density in the brain. However, the recent discovery of CB(2) receptors in the brain, particularly in the midbrain dopamine neurons, has challen...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Spiller, Krista J., Bi, Guo‐hua, He, Yi, Galaj, Ewa, Gardner, Eliot L., Xi, Zheng‐Xiong
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468271/
https://ncbi.nlm.nih.gov/pubmed/30767215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14625
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