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Cannabinoid CB(1) and CB(2) receptor mechanisms underlie cannabis reward and aversion in rats

BACKGROUND AND PURPOSE: Endocannabinoids are critically involved in brain reward functions, mediated by activation of CB(1) receptors, reflecting their high density in the brain. However, the recent discovery of CB(2) receptors in the brain, particularly in the midbrain dopamine neurons, has challen...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Spiller, Krista J., Bi, Guo‐hua, He, Yi, Galaj, Ewa, Gardner, Eliot L., Xi, Zheng‐Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468271/
https://ncbi.nlm.nih.gov/pubmed/30767215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14625
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