Dissecting the role of CB(1) and CB(2) receptors in cannabinoid reward versus aversion using transgenic CB(1)- and CB(2)-knockout mice

Cannabinoids produce both rewarding and aversive effects in humans and experimental animals. However, the mechanisms underlying these conflicting findings are unclear. Here we examined the potential involvement of CB(1) and CB(2) receptors in cannabinoid action using transgenic CB(1)-knockout (CB(1)...

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Veröffentlicht in:Eur Neuropsychopharmacol
Hauptverfasser: Li, Xia, Hempel, Briana J., Yang, Hong-Ju, Han, Xiao, Bi, Guo-Hua, Gardner, Eliot L., Xi, Zheng-Xiong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854511/
https://ncbi.nlm.nih.gov/pubmed/33334652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2020.11.019
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