Epilepsy Gene Therapy Using an Engineered Potassium Channel

Refractory focal epilepsy is a devastating disease for which there is frequently no effective treatment. Gene therapy represents a promising alternative, but treating epilepsy in this way involves irreversible changes to brain tissue, so vector design must be carefully optimized to guarantee safety...

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Pubblicato in:J Neurosci
Autori principali: Snowball, Albert, Chabrol, Elodie, Wykes, Robert C., Shekh-Ahmad, Tawfeeq, Cornford, Jonathan H., Lieb, Andreas, Hughes, Michael P., Massaro, Giulia, Rahim, Ahad A., Hashemi, Kevan S., Kullmann, Dimitri M., Walker, Matthew C., Schorge, Stephanie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2019
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468110/
https://ncbi.nlm.nih.gov/pubmed/30755487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1143-18.2019
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