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Biochemical autoregulatory gene therapy for focal epilepsy

Despite the introduction of over a dozen new antiepileptic drugs in the last 20 years, approximately one third of people who develop epilepsy continue to have seizures on mono- or polytherapy1. Viral-vector mediated gene transfer offers the opportunity to design a rational treatment that builds on m...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Lieb, Andreas, Qiu, Yichen, Dixon, Christine L, Heller, Janosch P, Walker, Matthew C, Schorge, Stephanie, Kullmann, Dimitri M
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152911/
https://ncbi.nlm.nih.gov/pubmed/29988123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0103-x
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