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Chemical–genetic attenuation of focal neocortical seizures

Focal epilepsy is commonly pharmacoresistant, and resective surgery is often contraindicated by proximity to eloquent cortex. Many patients have no effective treatment options. Gene therapy allows cell-type specific inhibition of neuronal excitability, but on-demand seizure suppression has only been...

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Main Authors: Kätzel, Dennis, Nicholson, Elizabeth, Schorge, Stephanie, Walker, Matthew C., Kullmann, Dimitri M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Pub. Group 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050272/
https://ncbi.nlm.nih.gov/pubmed/24866701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4847
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