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Chemical–genetic attenuation of focal neocortical seizures

Focal epilepsy is commonly pharmacoresistant, and resective surgery is often contraindicated by proximity to eloquent cortex. Many patients have no effective treatment options. Gene therapy allows cell-type specific inhibition of neuronal excitability, but on-demand seizure suppression has only been...

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Podrobná bibliografie
Hlavní autoři: Kätzel, Dennis, Nicholson, Elizabeth, Schorge, Stephanie, Walker, Matthew C., Kullmann, Dimitri M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050272/
https://ncbi.nlm.nih.gov/pubmed/24866701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4847
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