Mitofusin 2 Participates in Mitophagy and Mitochondrial Fusion Against Angiotensin II-Induced Cardiomyocyte Injury

BACKGROUND: Mitochondrial dynamics play a critical role in mitochondrial function. The mitofusin 2 (MFN2) gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion to maintain and operate the mitochondrial network. Moreover, MFN2 is essential for mitophagy. In Ang II-in...

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Vydáno v:Front Physiol
Hlavní autoři: Xiong, Wenjun, Ma, Zhuang, An, Dongqi, Liu, Zuheng, Cai, Wanqiang, Bai, Yujia, Zhan, Qiong, Lai, Wenyan, Zeng, Qingchun, Ren, Hao, Xu, Dingli
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468045/
https://ncbi.nlm.nih.gov/pubmed/31024347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00411
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