Estrogen receptor beta enhances chemotherapy response of GBM cells by down regulating DNA damage response pathways

Glioblastoma (GBM) is the most commonly diagnosed brain tumor that exhibit high mortality rate and chemotherapy resistance is a major clinical problem. Recent studies suggest that estrogen receptor beta (ERβ), may function as a tumor suppressor in GBM. However, the mechanism(s) by which ERβ contribu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhou, Mei, Sareddy, Gangadhara R., Li, Mengxing, Liu, Jinyou, Luo, Yiliao, Venkata, Prabhakar Pitta, Viswanadhapalli, Suryavathi, Tekmal, Rajeshwar R., Brenner, Andrew, Vadlamudi, Ratna K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467924/
https://ncbi.nlm.nih.gov/pubmed/30992459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42313-8
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