Estrogen receptor beta enhances chemotherapy response of GBM cells by down regulating DNA damage response pathways

Glioblastoma (GBM) is the most commonly diagnosed brain tumor that exhibit high mortality rate and chemotherapy resistance is a major clinical problem. Recent studies suggest that estrogen receptor beta (ERβ), may function as a tumor suppressor in GBM. However, the mechanism(s) by which ERβ contribu...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Zhou, Mei, Sareddy, Gangadhara R., Li, Mengxing, Liu, Jinyou, Luo, Yiliao, Venkata, Prabhakar Pitta, Viswanadhapalli, Suryavathi, Tekmal, Rajeshwar R., Brenner, Andrew, Vadlamudi, Ratna K.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2019
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467924/
https://ncbi.nlm.nih.gov/pubmed/30992459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42313-8
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