Selective Estrogen Receptor β Agonist LY500307 as a Novel Therapeutic Agent for Glioblastoma

Glioblastomas (GBM), deadly brain tumors, have greater incidence in males than females. Epidemiological evidence supports a tumor suppressive role of estrogen; however, estrogen as a potential therapy for GBM is limited due to safety concerns. Since GBM express ERβ, a second receptor for estrogen, t...

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Published in:Sci Rep
Main Authors: Sareddy, Gangadhara R., Li, Xiaonan, Liu, Jinyou, Viswanadhapalli, Suryavathi, Garcia, Lauren, Gruslova, Aleksandra, Cavazos, David, Garcia, Mike, Strom, Anders M., Gustafsson, Jan-Ake, Tekmal, Rajeshwar Rao, Brenner, Andrew, Vadlamudi, Ratna K.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850367/
https://ncbi.nlm.nih.gov/pubmed/27126081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24185
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