A carregar...
Structure-activity relationships of rationally designed ritonavir analogs: Impact of side-group stereochemistry, head-group spacing, and backbone composition on the interaction with CYP3A4
In a continuing effort to identify structural attributes required for strong binding and potent inhibition of human drug-metabolizing CYP3A4, we designed ten ritonavir-like analogs differing in the side-group stereochemistry, backbone atomic composition, and head-group spacing. All analogs had pyrid...
Na minha lista:
| Publicado no: | Biochemistry |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6467766/ https://ncbi.nlm.nih.gov/pubmed/30912932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00156 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|