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Interaction of human drug-metabolizing CYP3A4 with small inhibitory molecules
Binding of small inhibitory compounds to human cytochrome P450 3A4 (CYP3A4) could intefere with drug metabolism and lead to drug-drug interactions, the underlying mechanism of which is not fully understood due to insufficient structural information. This study investigated the interaction of recombi...
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| Publicado no: | Biochemistry |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6448587/ https://ncbi.nlm.nih.gov/pubmed/30676743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01221 |
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