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GENETICALLY-ENGINEERED PIGS AS SOURCES FOR CLINICAL RED BLOOD CELL TRANSFUSION: WHAT PATHOBIOLOGICAL BARRIERS NEED TO BE OVERCOME?

An alternative to human red blood cells (RBCs) for clinical transfusion would be advantageous, particularly in situations of massive acute blood loss (where availability and compatibility are limited) or chronic hematologic diseases requiring frequent transfusions (resulting in alloimmunization). Id...

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Detalhes bibliográficos
Publicado no:Blood Rev
Main Authors: Smood, Benjamin, Hara, Hidetaka, Schoel, Leah J., Cooper, David K.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467751/
https://ncbi.nlm.nih.gov/pubmed/30711308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.blre.2019.01.003
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