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IN SEARCH OF THE IDEAL VALVE: OPTIMIZING GENETIC MODIFICATIONS TO PREVENT BIOPROSTHETIC DEGENERATION

BACKGROUND: Bioprosthetic heart valves undergo structural degeneration and calcification. Similarities exist in the histopathologic features of explanted bioprosthetic valves and rejected pig tissues and organs after xenotransplantation into nonhuman primates. The development of more durable biopros...

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Detalhes bibliográficos
Publicado no:Ann Thorac Surg
Main Authors: Smood, Benjamin, Hara, Hidetaka, Cleveland, David, Cooper, David K.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656597/
https://ncbi.nlm.nih.gov/pubmed/30836101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2019.01.054
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