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Fluorescing Isofunctional Ribonucleosides: Assessing Adenosine Deaminase Activity and Inhibition

The enzymatic conversion of isothiazolo[4,3-d]pyrimidine based adenosine ((tz)A) and 2-aminoadenosine ((tz)2-AA) analogues to the corresponding isothiazolo[4,3-d]pyrimidine based inosine ((tz)I) and guanosine ((tz)G) derivatives is evaluated and compared to the conversion of native adenosine to inos...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chembiochem
Main Authors: Ludford, Paul T., Rovira, Alexander R., Fin, Andrea, Tor, Yitzhak
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467514/
https://ncbi.nlm.nih.gov/pubmed/30566279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800665
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