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Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala

Oxytocin administration has been reported to decrease consumption, withdrawal, and drug-seeking associated with several drugs of abuse and thus represents a promising pharmacological approach to treat drug addiction. We used an established rat model of alcohol dependence to investigate oxytocin’s ef...

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書誌詳細
出版年:PLoS Biol
主要な著者: Tunstall, Brendan J., Kirson, Dean, Zallar, Lia J., McConnell, Sam A., Vendruscolo, Janaina C. M., Ho, Chelsea P., Oleata, Christopher S., Khom, Sophia, Manning, Maurice, Lee, Mary R., Leggio, Lorenzo, Koob, George F., Roberto, Marisa, Vendruscolo, Leandro F.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467366/
https://ncbi.nlm.nih.gov/pubmed/30990816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006421
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