Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala

Oxytocin administration has been reported to decrease consumption, withdrawal, and drug-seeking associated with several drugs of abuse and thus represents a promising pharmacological approach to treat drug addiction. We used an established rat model of alcohol dependence to investigate oxytocin’s ef...

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Опубликовано в: :PLoS Biol
Главные авторы: Tunstall, Brendan J., Kirson, Dean, Zallar, Lia J., McConnell, Sam A., Vendruscolo, Janaina C. M., Ho, Chelsea P., Oleata, Christopher S., Khom, Sophia, Manning, Maurice, Lee, Mary R., Leggio, Lorenzo, Koob, George F., Roberto, Marisa, Vendruscolo, Leandro F.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467366/
https://ncbi.nlm.nih.gov/pubmed/30990816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006421
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