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Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala

Oxytocin administration has been reported to decrease consumption, withdrawal, and drug-seeking associated with several drugs of abuse and thus represents a promising pharmacological approach to treat drug addiction. We used an established rat model of alcohol dependence to investigate oxytocin’s ef...

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Bibliografske podrobnosti
izdano v:PLoS Biol
Main Authors: Tunstall, Brendan J., Kirson, Dean, Zallar, Lia J., McConnell, Sam A., Vendruscolo, Janaina C. M., Ho, Chelsea P., Oleata, Christopher S., Khom, Sophia, Manning, Maurice, Lee, Mary R., Leggio, Lorenzo, Koob, George F., Roberto, Marisa, Vendruscolo, Leandro F.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467366/
https://ncbi.nlm.nih.gov/pubmed/30990816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006421
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