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Diarylcarbonates are a new class of deubiquitinating enzyme inhibitors
Promiscuous inhibitors of tyrosine protein kinases, proteases and phosphatases are useful reagents for probing regulatory pathways and stabilizing lysates as well as starting points for the design of more targeted agents. Ubiquitination regulates many critical cellular processes, and promiscuous inh...
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| Publicat a: | Bioorg Med Chem Lett |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6467287/ https://ncbi.nlm.nih.gov/pubmed/30528168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.11.055 |
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