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MECHANISTIC ROLE OF THE CALCIUM-DEPENDENT PROTEASE CALPAIN IN THE ENDOTHELIAL DYSFUNCTION INDUCED BY MYELOPEROXIDASE
Myeloperoxidase (MPO) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction. The molecular mechanisms of the endothelial damaging action of MPO remain though largely elusive. Calpain is a calcium-d...
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| Publicado no: | Hypertension |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6467284/ https://ncbi.nlm.nih.gov/pubmed/29507101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10305 |
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