Caspase-3 Substrates for Noninvasive Pharmacodynamic Imaging of Apoptosis by PET/CT

Quantitative imaging of apoptosis in vivo could enable real-time monitoring of acute cell death pathologies such as traumatic brain injury, as well as the efficacy and safety of cancer therapy. Here, we describe the development and validation of F-18-labeled caspase-3 substrates for PET/CT imaging o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioconjug Chem
Prif Awduron: Engel, Brian J., Gammon, Seth T., Chaudhari, Rajan, Lu, Zhen, Pisaneschi, Federica, Yang, Hailing, Ornelas, Argentina, Yan, Victoria, Kelderhouse, Lindsay, Najjar, Amer M., Tong, William P., Zhang, Shuxing, Piwnica-Worms, David, Bast, Robert C., Millward, Steven W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467260/
https://ncbi.nlm.nih.gov/pubmed/30168713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.8b00514
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