RNA and Toll-Like Receptor 7 License the Generation of Superior Secondary Plasma Cells at Multiple Levels in a B Cell Intrinsic Fashion

Secondary plasma cells (PCs) originate from memory B cells and produce increased levels of antibodies with higher affinity compared to PCs generated during primary responses. Here we demonstrate that virus-like particles (VLPs) only induce secondary PCs in the presence of toll-like receptor (TLR) 7...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Krueger, Caroline C., Thoms, Franziska, Keller, Elsbeth, Leoratti, Fabiana M. S., Vogel, Monique, Bachmann, Martin F.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467167/
https://ncbi.nlm.nih.gov/pubmed/31024563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00736
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