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Inhibition Mechanism of Urease by Au(III) Compounds Unveiled by X-ray Diffraction Analysis

[Image: see text] The nickel-dependent enzyme urease is a virulence factor for a large number of critical human pathogens, making this enzyme a potential target of therapeutics for the treatment of resistant bacterial infections. In the search for novel urease inhibitors, five selected coordination...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Mazzei, Luca, Wenzel, Margot N., Cianci, Michele, Palombo, Marta, Casini, Angela, Ciurli, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466819/
https://ncbi.nlm.nih.gov/pubmed/30996797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00585
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