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RNA-sequencing reveals altered skeletal muscle contraction, E3 ligases, autophagy, apoptosis, and chaperone expression in patients with critical illness myopathy

BACKGROUND: Critical illness myopathy (CIM) is associated with severe skeletal muscle wasting and impaired function in intensive care unit (ICU) patients. The mechanisms underlying CIM remain incompletely understood. To elucidate the biological activities occurring at the transcriptional level in th...

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Detalhes bibliográficos
Publicado no:Skelet Muscle
Main Authors: Llano-Diez, Monica, Fury, Wen, Okamoto, Haruka, Bai, Yu, Gromada, Jesper, Larsson, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466682/
https://ncbi.nlm.nih.gov/pubmed/30992050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-019-0194-1
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