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RNA-sequencing reveals altered skeletal muscle contraction, E3 ligases, autophagy, apoptosis, and chaperone expression in patients with critical illness myopathy

BACKGROUND: Critical illness myopathy (CIM) is associated with severe skeletal muscle wasting and impaired function in intensive care unit (ICU) patients. The mechanisms underlying CIM remain incompletely understood. To elucidate the biological activities occurring at the transcriptional level in th...

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Bibliografske podrobnosti
izdano v:Skelet Muscle
Main Authors: Llano-Diez, Monica, Fury, Wen, Okamoto, Haruka, Bai, Yu, Gromada, Jesper, Larsson, Lars
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466682/
https://ncbi.nlm.nih.gov/pubmed/30992050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-019-0194-1
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