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RNA-sequencing reveals altered skeletal muscle contraction, E3 ligases, autophagy, apoptosis, and chaperone expression in patients with critical illness myopathy

BACKGROUND: Critical illness myopathy (CIM) is associated with severe skeletal muscle wasting and impaired function in intensive care unit (ICU) patients. The mechanisms underlying CIM remain incompletely understood. To elucidate the biological activities occurring at the transcriptional level in th...

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Podrobná bibliografie
Vydáno v:Skelet Muscle
Hlavní autoři: Llano-Diez, Monica, Fury, Wen, Okamoto, Haruka, Bai, Yu, Gromada, Jesper, Larsson, Lars
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466682/
https://ncbi.nlm.nih.gov/pubmed/30992050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-019-0194-1
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