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Prion and Prion-Like Protein Strains: Deciphering the Molecular Basis of Heterogeneity in Neurodegeneration

Increasing evidence suggests that neurodegenerative disorders share a common pathogenic feature: the presence of deposits of misfolded proteins with altered physicochemical properties in the Central Nervous System. Despite a lack of infectivity, experimental data show that the replication and propag...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Scialò, Carlo, De Cecco, Elena, Manganotti, Paolo, Legname, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466326/
https://ncbi.nlm.nih.gov/pubmed/30875755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11030261
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