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The prion strain phenomenon: Molecular basis and unprecedented features

Prions are unconventional infectious agents responsible for transmissible spongiform encephalopathies. Compelling evidences indicate that prions are composed exclusively by a misfolded form of the prion protein (PrP(Sc)) that replicates in the absence of nucleic acids. One of the most challenging pr...

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Detalhes bibliográficos
Main Authors: Morales, Rodrigo, Abid, Karim, Soto, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597801/
https://ncbi.nlm.nih.gov/pubmed/17254754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2006.12.006
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