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The anticancer drug–DNA complex: Femtosecond primary dynamics for anthracycline antibiotics function
The anthracycline–DNA complex, which is a potent agent for cancer chemotherapy, has a unique intercalating molecular structure with preference to the GC bases of DNA, as shown by Rich's group in studies of single-crystal x-ray diffraction. Understanding cytotoxicity and its photoenhancement req...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The National Academy of Sciences
2001
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC64661/ https://ncbi.nlm.nih.gov/pubmed/11724924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241509698 |
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