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The anticancer drug–DNA complex: Femtosecond primary dynamics for anthracycline antibiotics function

The anthracycline–DNA complex, which is a potent agent for cancer chemotherapy, has a unique intercalating molecular structure with preference to the GC bases of DNA, as shown by Rich's group in studies of single-crystal x-ray diffraction. Understanding cytotoxicity and its photoenhancement req...

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Bibliografische gegevens
Hoofdauteurs: Qu, Xiaogang, Wan, Chaozhi, Becker, Hans-Christian, Zhong, Dongping, Zewail, Ahmed H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC64661/
https://ncbi.nlm.nih.gov/pubmed/11724924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241509698
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