The anticancer drug–DNA complex: Femtosecond primary dynamics for anthracycline antibiotics function

The anthracycline–DNA complex, which is a potent agent for cancer chemotherapy, has a unique intercalating molecular structure with preference to the GC bases of DNA, as shown by Rich's group in studies of single-crystal x-ray diffraction. Understanding cytotoxicity and its photoenhancement requires...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Qu, Xiaogang, Wan, Chaozhi, Becker, Hans-Christian, Zhong, Dongping, Zewail, Ahmed H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Physical Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64661/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11724924/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.241509698
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