Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling

Early childhood is a critical period for development, and early life stress may increase the risk of gastrointestinal diseases including irritable bowel syndrome (IBS). In rodents, neonatal maternal separation (NMS) induces bowel dysfunctions that resemble IBS. However, the underlying mechanisms rem...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wong, Hoi Leong Xavier, Qin, Hong-yan, Tsang, Siu Wai, Zuo, Xiao, Che, Sijia, Chow, Chi Fung Willis, Li, Xi, Xiao, Hai-tao, Zhao, Ling, Huang, Tao, Lin, Cheng Yuan, Kwan, Hiu Yee, Yang, Tao, Longo, Frank M., Lyu, Aiping, Bian, Zhao-xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465335/
https://ncbi.nlm.nih.gov/pubmed/30988299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09744-3
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