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Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling

Early childhood is a critical period for development, and early life stress may increase the risk of gastrointestinal diseases including irritable bowel syndrome (IBS). In rodents, neonatal maternal separation (NMS) induces bowel dysfunctions that resemble IBS. However, the underlying mechanisms rem...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Wong, Hoi Leong Xavier, Qin, Hong-yan, Tsang, Siu Wai, Zuo, Xiao, Che, Sijia, Chow, Chi Fung Willis, Li, Xi, Xiao, Hai-tao, Zhao, Ling, Huang, Tao, Lin, Cheng Yuan, Kwan, Hiu Yee, Yang, Tao, Longo, Frank M., Lyu, Aiping, Bian, Zhao-xiang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465335/
https://ncbi.nlm.nih.gov/pubmed/30988299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09744-3
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