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Luteolin promotes apoptotic cell death via upregulation of Nrf2 expression by DNA demethylase and the interaction of Nrf2 with p53 in human colon cancer cells

Luteolin, a dietary flavone, modulates various signaling pathways involved in carcinogenesis. In this study, we investigated the molecular mechanism that underlies the apoptotic effects of luteolin mediated by DNA demethylation of the nuclear factor erythroid 2-related factor 2 (Nrf2) promoter and t...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Exp Mol Med
Asıl Yazarlar: Kang, Kyoung Ah, Piao, Mei Jing, Hyun, Yu Jae, Zhen, Ao Xuan, Cho, Suk Ju, Ahn, Mee Jung, Yi, Joo Mi, Hyun, Jin Won
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465248/
https://ncbi.nlm.nih.gov/pubmed/30988303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0238-y
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