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Impressionist portraits of mitotic exit: APC/C, K11-linked ubiquitin chains and Cezanne

The Anaphase-Promoting Complex/Cyclosome (APC/C) is an E3 ubiquitin ligase and a key regulator of cell cycle progression. By triggering the degradation of mitotic cyclins, APC/C controls cell cycle-dependent oscillations in cyclin-dependent kinase (CDK) activity. Thus, the dynamic activities of both...

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Detalles Bibliográficos
Publicado en:Cell Cycle
Main Authors: Bonacci, Thomas, Emanuele, Michael J
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464587/
https://ncbi.nlm.nih.gov/pubmed/30874463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1593646
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