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Platelet Protein Disulfide Isomerase Promotes Glycoprotein Ibα-Mediated Platelet-Neutrophil Interactions Under Thromboinflammatory Conditions

BACKGROUND: Platelet-neutrophil interactions contribute to vascular occlusion and tissue damage in thromboinflammatory disease. Platelet glycoprotein Ibα (GPIbα), a key receptor for cell-cell interactions, is believed to be constitutively active for ligand-binding. Here we established the role of pl...

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Dettagli Bibliografici
Pubblicato in:Circulation
Autori principali: Li, Jing, Kim, Kyungho, Jeong, Si-Yeon, Chiu, Joyce, Xiong, Bei, Petukhov, Pavel A., Dai, Xiangrong, Li, Xiaoyi, Andrews, Robert K., Du, Xiaoping, Hogg, Philip J., Cho, Jaehyung
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464389/
https://ncbi.nlm.nih.gov/pubmed/30586735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.118.036323
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