Asparagine 905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate–induced activation of ATP8A2 dephosphorylation

The P-type ATPase protein family includes, in addition to ion pumps such as Ca(2+)-ATPase and Na(+),K(+)-ATPase, also phospholipid flippases that transfer phospholipids between membrane leaflets. P-type ATPase ion pumps translocate their substrates occluded between helices in the center of the trans...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Mikkelsen, Stine A., Mogensen, Louise S., Vilsen, Bente, Molday, Robert S., Vestergaard, Anna L., Andersen, Jens Peter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2019
Gaiak:
Membrane Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463696/
https://ncbi.nlm.nih.gov/pubmed/30760526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007240
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