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Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P(4)-ATPase ATP8A2
ATP8A2 is a P(4)-ATPase (“flippase”) located in membranes of retinal photoreceptors, brain cells, and testis, where it mediates transport of aminophospholipids toward the cytoplasmic leaflet. It has long been an enigma whether the mechanism of P(4)-ATPases resembles that of the well-characterized ca...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277108/ https://ncbi.nlm.nih.gov/pubmed/22307598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108862109 |
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