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Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P(4)-ATPase ATP8A2

ATP8A2 is a P(4)-ATPase (“flippase”) located in membranes of retinal photoreceptors, brain cells, and testis, where it mediates transport of aminophospholipids toward the cytoplasmic leaflet. It has long been an enigma whether the mechanism of P(4)-ATPases resembles that of the well-characterized ca...

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Hlavní autoři: Coleman, Jonathan A., Vestergaard, Anna L., Molday, Robert S., Vilsen, Bente, Peter Andersen, Jens
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277108/
https://ncbi.nlm.nih.gov/pubmed/22307598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108862109
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