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Disease mutations reveal residues critical to the interaction of P4-ATPases with lipid substrates
Phospholipid flippases (P(4)-ATPases) translocate specific phospholipids from the exoplasmic to the cytoplasmic leaflet of membranes. While there is good evidence that the overall molecular structure of flippases is similar to that of P-type ATPase ion-pumps, the transport pathway for the “giant” li...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5585164/ https://ncbi.nlm.nih.gov/pubmed/28874751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10741-z |
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