Ribonucleotide reductase M2 promotes RNA replication of hepatitis C virus by protecting NS5B protein from hPLIC1-dependent proteasomal degradation

Hepatitis C virus (HCV) establishes a chronic infection that can lead to cirrhosis and hepatocellular carcinoma. The HCV life cycle is closely associated with host factors that promote or restrict viral replication, the characterization of which could help to identify potential therapeutic targets....

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Kitab, Bouchra, Satoh, Masaaki, Ohmori, Yusuke, Munakata, Tsubasa, Sudoh, Masayuki, Kohara, Michinori, Tsukiyama-Kohara, Kyoko
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463693/
https://ncbi.nlm.nih.gov/pubmed/30755480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004397
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items