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Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumors: Small Steps Toward Personalized Medicine?

Various molecular triggers define heterogeneous subsets of gastrointestinal stromal tumors (GISTs), differing in clinical behavior and drug sensitivity. KIT/PDGFRA-wild-type GISTs, including those succinate dehydrogenase (SDH)-deficient, are overall unresponsive to the tyrosine kinase inhibitors com...

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Podrobná bibliografie
Vydáno v:Epigenet Insights
Hlavní autoři: Ravegnini, Gloria, Ricci, Riccardo
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463228/
https://ncbi.nlm.nih.gov/pubmed/31020269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2516865719842534
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