Flagellin-mediated activation of IL-33-ST2 signaling by a pathobiont promotes intestinal fibrosis

Intestinal fibrosis is a severe complication in patients with Crohn’s disease (CD). Unfortunately, the trigger leading to the development of intestinal fibrosis in the context of CD remains elusive. Here, we show that colonization by a CD-associated pathobiont adherent-invasive Escherichia coli (AIE...

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Bibliografische gegevens
Gepubliceerd in:Mucosal Immunol
Hoofdauteurs: Imai, Jin, Kitamoto, Sho, Sugihara, Kohei, Nagao-Kitamoto, Hiroko, Hayashi, Atsushi, Morhardt, Tina L., Kuffa, Peter, Higgins, Peter D. R., Barnich, Nicolas, Kamada, Nobuhiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462251/
https://ncbi.nlm.nih.gov/pubmed/30742042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-019-0138-4
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