Flagellin-mediated activation of IL-33-ST2 signaling by a pathobiont promotes intestinal fibrosis

Intestinal fibrosis is a severe complication in patients with Crohn’s disease (CD). Unfortunately, the trigger leading to the development of intestinal fibrosis in the context of CD remains elusive. Here, we show that colonization by a CD-associated pathobiont adherent-invasive Escherichia coli (AIE...

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Bibliografiske detaljer
Udgivet i:Mucosal Immunol
Main Authors: Imai, Jin, Kitamoto, Sho, Sugihara, Kohei, Nagao-Kitamoto, Hiroko, Hayashi, Atsushi, Morhardt, Tina L., Kuffa, Peter, Higgins, Peter D. R., Barnich, Nicolas, Kamada, Nobuhiko
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462251/
https://ncbi.nlm.nih.gov/pubmed/30742042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-019-0138-4
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