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The non-transcriptional activity of IRF3 modulates hepatic immune cell populations in acute on chronic ethanol administration in mice
BACKGROUND & AIMS: Interferon regulatory factor 3 (IRF3) is a transcription factor mediating anti-viral responses, yet recent evidence indicates that IRF3 also has critical non-transcriptional functions, including activating RIG-I-like receptors-induced IRF-3-mediated pathway of apoptosis (RIPA)...
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| Опубликовано в: : | J Hepatol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462245/ https://ncbi.nlm.nih.gov/pubmed/30710579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2019.01.021 |
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