Cargando...
Meet the terminator: the phosphatase PP2A puts brakes on IRF-3 activation
Cellular interferon response to microbial infection is transient; In a recently paper in Immunity, Long et al identifies PP2A phosphatase as a deactivator of phospho-IRF-3, the key transcription factor for interferon synthesis, thus providing one basis for the observed transiency.
Guardado en:
| Autores principales: | , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053166/ https://ncbi.nlm.nih.gov/pubmed/24766884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.04.008 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|