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Structural insights into the subtype-selective antagonist binding to the M2 muscarinic receptor
Human muscarinic receptor, M(2) is one of the five subtypes of muscarinic receptors belonging to the family of G protein-coupled receptors. Muscarinic receptors are targets for multiple neurodegenerative diseases. The challenge has been designing subtype selective ligands against one of the five mus...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Chem Biol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462224/ https://ncbi.nlm.nih.gov/pubmed/30420692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0152-y |
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