Chargement en cours...
Risk variants disrupting enhancers of T(H)1 and T(REG) cells in type 1 diabetes
Genome-wide association studies (GWASs) have revealed 59 genomic loci associated with type 1 diabetes (T1D). Functional interpretation of the SNPs located in the noncoding region of these loci remains challenging. We perform epigenomic profiling of two enhancer marks, H3K4me1 and H3K27ac, using prim...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
|---|---|
| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2019
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462079/ https://ncbi.nlm.nih.gov/pubmed/30910956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815336116 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|